Cadherins and their connections: adhesion junctions have broader functions

MS Steinberg, PM McNutt - Current opinion in cell biology, 1999 - Elsevier
MS Steinberg, PM McNutt
Current opinion in cell biology, 1999Elsevier
Cadherins—a family of cell–cell adhesion molecules—are linked to the actin cytoskeleton
via intervening proteins. Recent results address molecular explanations for observed
cadherin behavior, point to signals that regulate adhesion by modulating elements of the
cadherin-associated complex, challenge the belief that different cadherins generally cannot
cross-adhere, and highlight instructive roles for cadherins in cell signaling and
differentiation.
Cadherins — a family of cell–cell adhesion molecules — are linked to the actin cytoskeleton via intervening proteins. Recent results address molecular explanations for observed cadherin behavior, point to signals that regulate adhesion by modulating elements of the cadherin-associated complex, challenge the belief that different cadherins generally cannot cross-adhere, and highlight instructive roles for cadherins in cell signaling and differentiation.
Elsevier