[HTML][HTML] Myosin V in the brain: mutations lead to neurological defects
GM Langford, BJ Molyneaux - Brain research reviews, 1998 - Elsevier
Astronauts experience differing degrees of locomotor disturbances including ataxia,
following space flight. The basis of microgravity-induced ataxia and locomotor dyswx
function are not well understood 59. Recent studies of ataxia in rats and mice caused by
mutations in myosin V, a neuronal myosin, may shed light on the molecular basis of ataxia in
human subjects. Myosin V is one of the most abundant myosins in neurons. Our
understanding of the mechanism by which mutations in this myosin leads to loss of neural …
following space flight. The basis of microgravity-induced ataxia and locomotor dyswx
function are not well understood 59. Recent studies of ataxia in rats and mice caused by
mutations in myosin V, a neuronal myosin, may shed light on the molecular basis of ataxia in
human subjects. Myosin V is one of the most abundant myosins in neurons. Our
understanding of the mechanism by which mutations in this myosin leads to loss of neural …