Δ9-THC stimulates food intake in Lewis rats: effects on chow, high-fat and sweet high-fat diets
JE Koch - Pharmacology Biochemistry and Behavior, 2001 - Elsevier
Free-feeding adult male Lewis rats were administered intraperitoneal (ip) Δ9-
tetrahydrocannabinol (THC) in doses of 0.5, 1.0 and 2.5 mg/kg, and effects on food intake
were measured at 1, 2, 4, 6 and 24 h postinjection. Rats were fed rat chow, a high-fat diet
(HF) or a high-fat sweetened (HFS) diet. Small increases in HF and HFS intake following
doses of 0.5 or 1.0 mg/kg were seen at 1, 2 and 4 h, but not 6 or 24 h compared to vehicle
intake. Increases following 0.5 and 1.0 mg/kg did not differ from each other at any time point …
tetrahydrocannabinol (THC) in doses of 0.5, 1.0 and 2.5 mg/kg, and effects on food intake
were measured at 1, 2, 4, 6 and 24 h postinjection. Rats were fed rat chow, a high-fat diet
(HF) or a high-fat sweetened (HFS) diet. Small increases in HF and HFS intake following
doses of 0.5 or 1.0 mg/kg were seen at 1, 2 and 4 h, but not 6 or 24 h compared to vehicle
intake. Increases following 0.5 and 1.0 mg/kg did not differ from each other at any time point …