[HTML][HTML] Large isoform of hepatitis delta antigen activates serum response factor-associated transcription
T Goto, N Kato, SK Ono-Nita, H Yoshida… - Journal of Biological …, 2000 - ASBMB
Hepatitis delta virus infection sometimes causes severe and fulminant hepatitis as a
coinfection or superinfection along with the hepatitis B virus. To elucidate the underlying
mechanism of injury caused by hepatitis delta virus, we examined whether two isoforms of
the hepatitis delta antigen (HDAg) had any effect on five well defined intracellular signal
transduction pathways: serum response factor (SRF)-, serum response element (SRE)-,
nuclear factor κB-, activator protein 1-, and cyclic AMP response element-dependent …
coinfection or superinfection along with the hepatitis B virus. To elucidate the underlying
mechanism of injury caused by hepatitis delta virus, we examined whether two isoforms of
the hepatitis delta antigen (HDAg) had any effect on five well defined intracellular signal
transduction pathways: serum response factor (SRF)-, serum response element (SRE)-,
nuclear factor κB-, activator protein 1-, and cyclic AMP response element-dependent …