Some properties of mouse platelets
WI Rosenblum, GH Nelson, CS Cockrell, EF Ellis - Thrombosis research, 1983 - Elsevier
Mouse platelets were aggregated by arachidonate, thrombin, collagen and ADP. In general
they were, like rat platelets, more aggregable in heparinized PRP than in citrated (3.8%)
PRP. Mouse platelets underwent the release reaction when aggregated by arachidonate,
collagen and thrombin, but not when stimulated by ADP. The aggregation of the platelets to
arachidonate was inhibited by cyclooxygenase inhibitors and by prostacyclin. Studies with
tritiated arachidonate showed that mouse platelets possess the lipoxygenase and …
they were, like rat platelets, more aggregable in heparinized PRP than in citrated (3.8%)
PRP. Mouse platelets underwent the release reaction when aggregated by arachidonate,
collagen and thrombin, but not when stimulated by ADP. The aggregation of the platelets to
arachidonate was inhibited by cyclooxygenase inhibitors and by prostacyclin. Studies with
tritiated arachidonate showed that mouse platelets possess the lipoxygenase and …
