[HTML][HTML] De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption

SQ Siler, RA Neese, MK Hellerstein - The American journal of clinical …, 1999 - Elsevier
Background Acute alcohol intake is associated with changes in plasma lipid concentrations
and whole-body lipid balances in humans. The quantitative roles of hepatic de novo
lipogenesis (DNL) and plasma acetate production in these changes have not been
established, however. Objective We used stable-isotope mass spectrometric methods with
indirect calorimetry to establish the metabolic basis of changes in whole-body lipid balances
in healthy men after consumption of 24 g alcohol. Design Eight healthy subjects were …