The cytotoxic T lymphocyte gene FIBLP with homology to fibrinogen β and γ subunits is also induced in mouse macrophages by IFN-γ
WP Lafuse, L Castle, D Brown, BS Zwilling - Cellular immunology, 1995 - Elsevier
To identify genes induced in mouse macrophages by IFN-γ a cDNA subtraction library of IFN-
γ-induced genes was screened. One of the clones, 36F2, was identified by DNA sequencing
as the FIBLP gene. The FIBLP (fibrinogen-like protein) gene is a T-lymphocyte-specific gene
that is expressed in mouse cytotoxic T lymphocytes but not in helper T lymphocytes or B
lymphocytes. The protein sequence shows a high homology to fibrinogen β and γ subunits.
The FIBLP gene is not expressed in unstimulated mouse peritoneal macrophages but is …
γ-induced genes was screened. One of the clones, 36F2, was identified by DNA sequencing
as the FIBLP gene. The FIBLP (fibrinogen-like protein) gene is a T-lymphocyte-specific gene
that is expressed in mouse cytotoxic T lymphocytes but not in helper T lymphocytes or B
lymphocytes. The protein sequence shows a high homology to fibrinogen β and γ subunits.
The FIBLP gene is not expressed in unstimulated mouse peritoneal macrophages but is …