Immunological relationship between streptococcus A polysaccharide and the structural glycoproteins of heart valve.
I Goldste1N, B Halpern, L Robert - Nature, 1967 - search.ebscohost.com
I Goldste1N, B Halpern, L Robert
Nature, 1967•search.ebscohost.comis the same for esters of amino-acids, fatty acids and even Page 1 44 enzyme and therefore not
limited to one particular orientation. The observation that the optimum size of the R-groups is
the same for esters of amino-acids, fatty acids and even of substituted phosphoric acid would
suggest that in productive complexes the R-groups of these esters are attached to the same
hydrophobic area on the enzyme surface. This, however, does not exclude the possibility
that part of the chymotrypsin molecules form unproductive complexes through combination of …
limited to one particular orientation. The observation that the optimum size of the R-groups is
the same for esters of amino-acids, fatty acids and even of substituted phosphoric acid would
suggest that in productive complexes the R-groups of these esters are attached to the same
hydrophobic area on the enzyme surface. This, however, does not exclude the possibility
that part of the chymotrypsin molecules form unproductive complexes through combination of …
Abstract
Streptococcal infections can cause rheumatic heart disease. Polysaccharide from group A streptococci may induce the production of antibodies by an animal which then react against its own valvular glycoproteins
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