[HTML][HTML] Determinants of trachoma endemicity using Chlamydia trachomatis ompA DNA sequencing
A six-year prospective study of Chlamydia trachomatis infection and ocular disease in
Tanzanian village children was conducted to identify the determinants of trachoma
endemicity using sequencing of ompA. Overall, 749 conjunctival samples were obtained,
with 176 children sampled in both 1989 and 1995. 31.1%(233/749) were positive by PCR-
enzyme immunoassay, and 76%(176/233) of the positives were sequenced in variable
domains (VD) 1 to 4 (22 children in both 1989 and 1995). Twenty-six ompA genotypes of …
Tanzanian village children was conducted to identify the determinants of trachoma
endemicity using sequencing of ompA. Overall, 749 conjunctival samples were obtained,
with 176 children sampled in both 1989 and 1995. 31.1%(233/749) were positive by PCR-
enzyme immunoassay, and 76%(176/233) of the positives were sequenced in variable
domains (VD) 1 to 4 (22 children in both 1989 and 1995). Twenty-six ompA genotypes of …