Regulation of transcription by MAP kinase cascades

R Treisman - Current opinion in cell biology, 1996 - Elsevier
R Treisman
Current opinion in cell biology, 1996Elsevier
Kinases belonging to the mitogen-activated protein kinase (MAPK) family are used
throughout evolution to control the cellular responses to external signals such as growth
factors, nutrient status, stress or inductive signals. Many important substrates for MAPKs are
transcription factors, and both the genetic and the biochemical links between MAPKs and
transcription factors are becoming increasingly well understood.
Kinases belonging to the mitogen-activated protein kinase (MAPK) family are used throughout evolution to control the cellular responses to external signals such as growth factors, nutrient status, stress or inductive signals. Many important substrates for MAPKs are transcription factors, and both the genetic and the biochemical links between MAPKs and transcription factors are becoming increasingly well understood.
Elsevier