Effect of statins on risk of coronary disease: a meta-analysis of randomized controlled trials
JC LaRosa, J He, S Vupputuri - Jama, 1999 - jamanetwork.com
ContextLowering low-density lipoprotein cholesterol (LDL-C) is known to reduce risk of
recurrent coronary heart disease in middle-aged men. However, this effect has been
uncertain in elderly people and women. ObjectiveTo estimate the risk reduction of coronary
heart disease and total mortality associated with statin drug treatment, particularly in elderly
individuals and women. Data SourcesTrials published in English-language journals were
retrieved by searching MEDLINE (1966–December 1998), bibliographies, and authors' …
recurrent coronary heart disease in middle-aged men. However, this effect has been
uncertain in elderly people and women. ObjectiveTo estimate the risk reduction of coronary
heart disease and total mortality associated with statin drug treatment, particularly in elderly
individuals and women. Data SourcesTrials published in English-language journals were
retrieved by searching MEDLINE (1966–December 1998), bibliographies, and authors' …