Novel Type of Staphylococcal Cassette Chromosome mec Identified in Community-Acquired Methicillin-Resistant Staphylococcus aureus Strains
XX Ma, T Ito, C Tiensasitorn, M Jamklang… - Antimicrobial agents …, 2002 - Am Soc Microbiol
XX Ma, T Ito, C Tiensasitorn, M Jamklang, P Chongtrakool, S Boyle-Vavra, RS Daum…
Antimicrobial agents and chemotherapy, 2002•Am Soc MicrobiolWe identified a new type of staphylococcal cassette chromosome mec (SCC mec) from two
community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains. The novel
element, designated type IV SCC mec, had a unique combination of the class B mec gene
complex and the type 2 ccr gene complex and was much smaller in size (21 to 24 kb) than
previously identified SCC mec elements of hospital-acquired MRSA. Consistent with the
strains' susceptibilities to various non-β-lactam antibiotics, the type IV SCC mec was devoid …
community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains. The novel
element, designated type IV SCC mec, had a unique combination of the class B mec gene
complex and the type 2 ccr gene complex and was much smaller in size (21 to 24 kb) than
previously identified SCC mec elements of hospital-acquired MRSA. Consistent with the
strains' susceptibilities to various non-β-lactam antibiotics, the type IV SCC mec was devoid …
Abstract
We identified a new type of staphylococcal cassette chromosome mec (SCCmec) from two community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains. The novel element, designated type IV SCCmec, had a unique combination of the class B mec gene complex and the type 2 ccr gene complex and was much smaller in size (21 to 24 kb) than previously identified SCCmec elements of hospital-acquired MRSA. Consistent with the strains' susceptibilities to various non-β-lactam antibiotics, the type IV SCCmec was devoid of any antibiotic resistance genes other than the mecA gene.
American Society for Microbiology