[HTML][HTML] Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon

JA Payne, JC Xu, M Haas, CY Lytle, D Ward… - Journal of Biological …, 1995 - ASBMB
By moving chloride into epithelial cells, the Na-K-Cl cotransporter aids transcellular
movement of chloride across both secretory and absorptive epithelia. Using cDNA probes
from the recently identified elasmobranch secretory Na-K-Cl cotransporter (sNKCC1)(Xu,
JC, Lytle, C. Zhu, TT, Payne, JA, Benz, E., and Forbush, B., III (1994) Proc. Natl. Acad. Sci.
91, 2201-2205), we have identified the human homologue. By screening cDNA libraries of a
human colonic carcinoma line, T84 cell, we identified a sequence of 4115 bases from …