[HTML][HTML] Macrophage colony-stimulating factor rapidly enhances β-migrating very low density lipoprotein metabolism in macrophages through activation of a Gi/o …

SC Whitman, A Daugherty, SR Post - Journal of Biological Chemistry, 2000 - ASBMB
Previous studies have examined lipoprotein metabolism by macrophages following
prolonged exposure (> 24 h) to macrophage colony-stimulating factor (M-CSF). Because M-
CSF activates several signaling pathways that could rapidly affect lipoprotein metabolism,
we examined whether acute exposure of macrophages to M-CSF alters the metabolism of
either native or modified lipoproteins. Acute incubation of cultured J774 macrophages and
resident mouse peritoneal macrophages with M-CSF markedly enhanced low density …