Integrin αIIbβ3 signaling in platelet adhesion and aggregation
LV Parise - Current opinion in cell biology, 1999 - Elsevier
LV Parise
Current opinion in cell biology, 1999•ElsevierIntracellular signals are received and generated by the αIIbβ3 integrin on platelets. Recent
advances have been made in the areas of agonist receptors that initiate platelet activation,
downstream signaling molecules (eg small G-proteins and kinases) and changes in ligand-
occupied αIIbβ3 that cause further signaling and clot retraction.
advances have been made in the areas of agonist receptors that initiate platelet activation,
downstream signaling molecules (eg small G-proteins and kinases) and changes in ligand-
occupied αIIbβ3 that cause further signaling and clot retraction.
Intracellular signals are received and generated by the αIIbβ3 integrin on platelets. Recent advances have been made in the areas of agonist receptors that initiate platelet activation, downstream signaling molecules (e.g. small G-proteins and kinases) and changes in ligand-occupied αIIbβ3 that cause further signaling and clot retraction.
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