Hereditary stomatocytosis and allied conditions represent a series of diseases in which
abnormal movements of univalent cations across the plasma membrane play an important
part in cellular disease. The primary problem lies not in the active transporters but in the
basal permeability of the membrane, which is always increased, and the extent of the
increase correlates with the cellular dysfunction. A number of structural abnormalities have
been described in these membranes, but the most consistent and convincing is the …