[HTML][HTML] CD39 Is an Ecto-(Ca2+, Mg2+)-apyrase (∗)
TF Wang, G Guidotti - Journal of Biological Chemistry, 1996 - ASBMB
CD39, a 70-to 100-kDa molecule expressed primarily on activated lymphoid cells, was
previously identified as a surface marker of Epstein Barr virus (EBV)-transformed B cells. In
this report, we show that an ecto-(Ca 2+, Mg 2+)-apyrase activity is present on EBV-
transformed B cells, but not on B or T lymphomas. The coincidence between CD39
expression and ecto-apyrase activity on immune cells suggests that CD39 may be an ecto-
apyrase. This supposition is supported by the observation that the amino acid sequence of …
previously identified as a surface marker of Epstein Barr virus (EBV)-transformed B cells. In
this report, we show that an ecto-(Ca 2+, Mg 2+)-apyrase activity is present on EBV-
transformed B cells, but not on B or T lymphomas. The coincidence between CD39
expression and ecto-apyrase activity on immune cells suggests that CD39 may be an ecto-
apyrase. This supposition is supported by the observation that the amino acid sequence of …