Oxysterol regulators of 3-hydroxy-3-methylglutaryl-CoA reductase in liver: effect of dietary cholesterol
SE Saucier, AA Kandutsch, AK Gayen… - Journal of Biological …, 1989 - ASBMB
Hepatic regulatory oxysterols were analyzed to determine which oxysterols were present in
livers of mice fed a cholesterol-free diet and whether repression of 3-hydroxy-3-
methylglutaryl-CoA reductase following cholesterol feeding was accompanied by an
increase in one or more oxysterols. Analysis of free and esterified sterols from mice fed a
cholesterol-free diet resulted in the identification and quantitation of six regulatory
oxysterols: 24-hydroxycholesterol, 25-hydroxycholesterol, 26-hydroxycholesterol, 7 α …
livers of mice fed a cholesterol-free diet and whether repression of 3-hydroxy-3-
methylglutaryl-CoA reductase following cholesterol feeding was accompanied by an
increase in one or more oxysterols. Analysis of free and esterified sterols from mice fed a
cholesterol-free diet resulted in the identification and quantitation of six regulatory
oxysterols: 24-hydroxycholesterol, 25-hydroxycholesterol, 26-hydroxycholesterol, 7 α …