Application of prostaglandin-profiling techniques to study the release of prostaglandins from the fetal lamb ductus arteriosus
CR Pace-Asciak, G Rangaraj - Biochimica et Biophysica Acta (BBA)-Lipids …, 1983 - Elsevier
Through gas chromatographic techniques with capillary columns and electron-capture
detection which allow the resolution of prostaglandins F 2α, D 2, E 2, thromboxane B 2 and 6-
ketoprostaglandin F 1α and their 15-keto-and 15-keto-13, 14-dihydro metabolites, we have
studied the release of these products from the ductus arteriosus in vitro. 6-Ketoprostaglandin
F 1α was the major product in the incubation fluid while 15-keto-13, 14-dihydro
prostaglandin F 2α was the major product in the tissue. Prostaglandin E 2 was almost …
detection which allow the resolution of prostaglandins F 2α, D 2, E 2, thromboxane B 2 and 6-
ketoprostaglandin F 1α and their 15-keto-and 15-keto-13, 14-dihydro metabolites, we have
studied the release of these products from the ductus arteriosus in vitro. 6-Ketoprostaglandin
F 1α was the major product in the incubation fluid while 15-keto-13, 14-dihydro
prostaglandin F 2α was the major product in the tissue. Prostaglandin E 2 was almost …