The persistent expression of a highly polysialylated NCAM in the dentate gyrus of the adult rat

T Seki, Y Arai - Neuroscience research, 1991 - Elsevier
The expression of a highly polysialylated form of the neural cell adhesion molecule (NCAM-
H), often termed 'embryonic NCAM', has been investigated in the hippocampal formation of
developing and adult rats. To determine the immunohistochemical localization of NCAM-H,
a monoclonal antibody that reacts with the polysialic acid portion of NCAM-H was used. In
the late embryonic and early postnatal periods, immunoreactivity for NCAM-H was found
throughout the hippocampal formation, except for the ventricular layer. Thereafter, the …