Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes: the MIRACL study: a randomized controlled trial

GG Schwartz, AG Olsson, MD Ezekowitz, P Ganz… - Jama, 2001 - jamanetwork.com
ContextPatients experience the highest rate of death and recurrent ischemic events during
the early period after an acute coronary syndrome, but it is not known whether early initiation
of treatment with a statin can reduce the occurrence of these early events. ObjectiveTo
determine whether treatment with atorvastatin, 80 mg/d, initiated 24 to 96 hours after an
acute coronary syndrome, reduces death and nonfatal ischemic events. Design and
SettingA randomized, double-blind trial conducted from May 1997 to September 1999, with …