Cardiovascular responses elicited by chemical stimulation of the rostral ventrolateral medulla in conscious, unrestrained rats
H Bachelard, SM Gardiner, T Bennett - Journal of the autonomic nervous …, 1990 - Elsevier
The cardiovascular effects of microinjection of l-glutamic acid into the rostral ventrolateral
medulla have been investigated in anaesthetized and in conscious, unrestrained rats. In
conscious rats l-glutamic acid (0.36, 1.2 and 2.4 nmol) produced significant increases in
blood pressure, generally accompanied by a bradycardia. A lower dose of l-glutamic acid
(0.12 nmol) had no effect on blood pressure or heart rate. The cardiovascular responses
elicited by l-glutamic acid (2.4 nmol) were completely abolished by intravenous infusion of …
medulla have been investigated in anaesthetized and in conscious, unrestrained rats. In
conscious rats l-glutamic acid (0.36, 1.2 and 2.4 nmol) produced significant increases in
blood pressure, generally accompanied by a bradycardia. A lower dose of l-glutamic acid
(0.12 nmol) had no effect on blood pressure or heart rate. The cardiovascular responses
elicited by l-glutamic acid (2.4 nmol) were completely abolished by intravenous infusion of …