The selectins and their ligands

SD Rosen, CR Bertozzi - Current opinion in cell biology, 1994 - Elsevier
Current opinion in cell biology, 1994Elsevier
The selectins are a family of carbohydrate-binding proteins, or lectins, that have stimulated
tremendous interest because of their involvement in a wide array of interactions between
leukocytes and endothelial cells. Highlights of recent progress include an extension of the
list of instances of selectin participation in inflammatory diseases, further definition of
selectin carbohydrate specificities, and identification of their carbohydrate-based ligands.
Abstract
The selectins are a family of carbohydrate-binding proteins, or lectins, that have stimulated tremendous interest because of their involvement in a wide array of interactions between leukocytes and endothelial cells. Highlights of recent progress include an extension of the list of instances of selectin participation in inflammatory diseases, further definition of selectin carbohydrate specificities, and identification of their carbohydrate-based ligands.
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