[HTML][HTML] Gene-specific regulation by general translation factors
TE Dever - Cell, 2002 - cell.com
Cell, 2002•cell.com
Protein synthesis is the ultimate step of gene expression and a key control point for
regulation. In particular, it enables cells to rapidly manipulate protein production without new
mRNA synthesis, processing, or export. Recent studies have enhanced our understanding
of the translation initiation process and helped elucidate how modifications of the general
translational machinery regulate gene-specific protein production.
regulation. In particular, it enables cells to rapidly manipulate protein production without new
mRNA synthesis, processing, or export. Recent studies have enhanced our understanding
of the translation initiation process and helped elucidate how modifications of the general
translational machinery regulate gene-specific protein production.
Abstract
Protein synthesis is the ultimate step of gene expression and a key control point for regulation. In particular, it enables cells to rapidly manipulate protein production without new mRNA synthesis, processing, or export. Recent studies have enhanced our understanding of the translation initiation process and helped elucidate how modifications of the general translational machinery regulate gene-specific protein production.
cell.com