Chemokines, lymphocytes and viruses: what goes around, comes around
PJ Nelson, AM Krensky - Current opinion in immunology, 1998 - Elsevier
PJ Nelson, AM Krensky
Current opinion in immunology, 1998•ElsevierChemokines are believed to be the long-sought soluble mediators of selective lymphocyte
recruitment. As most selectin—integrin interactions are nonselective, it is thought that the
discrimination seen during lymphocyte infiltration into tissues is brought about by the actions
of distinct chemokines. Developments over the past year have demonstrated the expanding
roles of these factors in lymphocyte chemoattraction, normal trafficking, and viral immunity.
recruitment. As most selectin—integrin interactions are nonselective, it is thought that the
discrimination seen during lymphocyte infiltration into tissues is brought about by the actions
of distinct chemokines. Developments over the past year have demonstrated the expanding
roles of these factors in lymphocyte chemoattraction, normal trafficking, and viral immunity.
Chemokines are believed to be the long-sought soluble mediators of selective lymphocyte recruitment. As most selectin—integrin interactions are nonselective, it is thought that the discrimination seen during lymphocyte infiltration into tissues is brought about by the actions of distinct chemokines. Developments over the past year have demonstrated the expanding roles of these factors in lymphocyte chemoattraction, normal trafficking, and viral immunity.
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