Structure of the gene encoding human liver cholesterol 7α-hydroxylase

M Nishimoto, M Noshiro, K Okuda - Biochimica et Biophysica Acta (BBA) …, 1993 - Elsevier
A human cholesterol 7α-hydroxylase gene spanning 17 kb in length which includes the
sequence 5′ flanking region (6. kb) and that of the entire transcriptional region (10.5 kb)
was obtained from two partially overlapping clones (ie, HG 18 and HG 17) of a human
genomic library. The exon-intron boundaries are completely identical with that of rat gene.
Several transcriptional factor recognition sequences were observed in the 5′ flanking
region.