Antigen presentation to CD8+ T cells: cross-priming in infectious diseases
JMM den Haan, MJ Bevan - Current opinion in immunology, 2001 - Elsevier
JMM den Haan, MJ Bevan
Current opinion in immunology, 2001•ElsevierRecent studies indicate that, in most types of infections, antigen presentation by
'professional'bone-marrow-derived cells is essential for priming pathogen-specific CD8+ T
cells. This is true even in the absence of direct infection of these cells, which indicates that
cross-priming is an essential component of the immune response against pathogens.
'professional'bone-marrow-derived cells is essential for priming pathogen-specific CD8+ T
cells. This is true even in the absence of direct infection of these cells, which indicates that
cross-priming is an essential component of the immune response against pathogens.
Recent studies indicate that, in most types of infections, antigen presentation by ‘professional’ bone-marrow-derived cells is essential for priming pathogen-specific CD8+ T cells. This is true even in the absence of direct infection of these cells, which indicates that cross-priming is an essential component of the immune response against pathogens.
Elsevier