Injection of anti-neuropeptide Y γ-globulin into the hypothalamic paraventricular nucleus decreases food intake in rats
T Shibasaki, T Oda, T Imaki, N Ling, H Demura - Brain research, 1993 - Elsevier
T Shibasaki, T Oda, T Imaki, N Ling, H Demura
Brain research, 1993•ElsevierThe effect of immunoneutralization of hypothalamic neuropeptide Y (NPY) on food intake
was examined to clarify the involvement of NPY in the control mechanism of feeding
behavior. Injection of anti-NPY γ-globulin into the bilateral hypothalamic paraventrcular
nuclei of 24-h food-deprived rats significantly inhibited food intake for 1 h after the injection
compared with rats that received normal rabbit γ-globulin. This result suggests that NPY in
the paraventricular nucleus plays a role in stimulating feeding behavior.
was examined to clarify the involvement of NPY in the control mechanism of feeding
behavior. Injection of anti-NPY γ-globulin into the bilateral hypothalamic paraventrcular
nuclei of 24-h food-deprived rats significantly inhibited food intake for 1 h after the injection
compared with rats that received normal rabbit γ-globulin. This result suggests that NPY in
the paraventricular nucleus plays a role in stimulating feeding behavior.
The effect of immunoneutralization of hypothalamic neuropeptide Y (NPY) on food intake was examined to clarify the involvement of NPY in the control mechanism of feeding behavior. Injection of anti-NPY γ-globulin into the bilateral hypothalamic paraventrcular nuclei of 24-h food-deprived rats significantly inhibited food intake for 1 h after the injection compared with rats that received normal rabbit γ-globulin. This result suggests that NPY in the paraventricular nucleus plays a role in stimulating feeding behavior.
Elsevier