[HTML][HTML] Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice
CT Coburn, FF Knapp, M Febbraio, AL Beets… - Journal of Biological …, 2000 - ASBMB
The transmembrane protein CD36 has been identified in isolated cell studies as a putative
transporter of long chain fatty acids. In humans, an association between CD36 deficiency
and defective myocardial uptake of the fatty acid analog 15-(p-iodophenyl)-3-(R, S)-methyl
pentadecanoic acid (BMIPP) has been reported. To determine whether this association
represents a causal link and to assess the physiological role of CD36, we compared tissue
uptake and metabolism of two iodinated fatty acid analogs BMIPP and 15-(p-iodophenyl) …
transporter of long chain fatty acids. In humans, an association between CD36 deficiency
and defective myocardial uptake of the fatty acid analog 15-(p-iodophenyl)-3-(R, S)-methyl
pentadecanoic acid (BMIPP) has been reported. To determine whether this association
represents a causal link and to assess the physiological role of CD36, we compared tissue
uptake and metabolism of two iodinated fatty acid analogs BMIPP and 15-(p-iodophenyl) …