[HTML][HTML] Purification of a cell-surface receptor for surfactant protein A
ZC Chroneos, R Abdolrasulnia, JA Whitsett… - Journal of Biological …, 1996 - ASBMB
In the present report we have characterized the binding of surfactant protein A (SP-A) to
bone marrow-derived macrophages, U937 cells, alveolar macrophages, and type II
epithelial cells. The binding of SP-A to all cell types is Ca 2+-dependent and trypsin-
sensitive, but type II cells express distinct Ca 2+-independent binding sites. The binding of
SP-A to macrophages is independent of known cell surface carbohydrate-specific receptors
and of glycoconjugate binding sites on the surface of the cells and is distinct from binding to …
bone marrow-derived macrophages, U937 cells, alveolar macrophages, and type II
epithelial cells. The binding of SP-A to all cell types is Ca 2+-dependent and trypsin-
sensitive, but type II cells express distinct Ca 2+-independent binding sites. The binding of
SP-A to macrophages is independent of known cell surface carbohydrate-specific receptors
and of glycoconjugate binding sites on the surface of the cells and is distinct from binding to …