An integrated genetic and physical map of the 650-kb region containing the congenital polycystic kidney (cpk) locus on mouse Chromosome 12
M Mrug, WJ Green, S DasGupta, DR Beier… - Cytogenetics and cell …, 2001 - karger.com
Cytogenetics and cell genetics, 2001•karger.com
Mice homozygous for the congenital polycystic kidney (cpk) mutation develop a rapidly
progressive form of polycystic kidney disease. We report an integrated genetic and physical
map of the 650-kb region containing the cpk locus and the exclusion of Rrm2 and Idb2 as
candidate cpk genes. Our study establishes the requisite foundation for positional cloning of
the cpk gene.
progressive form of polycystic kidney disease. We report an integrated genetic and physical
map of the 650-kb region containing the cpk locus and the exclusion of Rrm2 and Idb2 as
candidate cpk genes. Our study establishes the requisite foundation for positional cloning of
the cpk gene.
Abstract
Mice homozygous for the congenital polycystic kidney (cpk) mutation develop a rapidly progressive form of polycystic kidney disease. We report an integrated genetic and physical map of the 650-kb region containing the cpk locus and the exclusion of Rrm2 and Idb2 as candidate cpk genes. Our study establishes the requisite foundation for positional cloning of the cpk gene.
Karger