Anaerobic production of alginate by Pseudomonas aeruginosa: alginate restricts diffusion of oxygen

DJ Hassett - Journal of bacteriology, 1996 - Am Soc Microbiol
Journal of bacteriology, 1996Am Soc Microbiol
Pseudomonas aeruginosa produced alginate and elevated algD (encoding GDPmannose 6-
dehydrogenase) transcription under strict anaerobic conditions, especially when using
nitrate as a terminal electron acceptor. Purified alginate added to bacterial suspensions
caused a decrease in growth, suggesting that alginate contributes to oxygen limitation for
the organism and likely for patients afflicted with the inherited autosomal disease cystic
fibrosis.
Pseudomonas aeruginosa produced alginate and elevated algD (encoding GDPmannose 6-dehydrogenase) transcription under strict anaerobic conditions, especially when using nitrate as a terminal electron acceptor. Purified alginate added to bacterial suspensions caused a decrease in growth, suggesting that alginate contributes to oxygen limitation for the organism and likely for patients afflicted with the inherited autosomal disease cystic fibrosis.
American Society for Microbiology