Chemokines participate in leukocyte infiltration, which plays a major role in glomerular injury
during immune complex glomerulonephritis (IC-GN). Because target cell expression of
chemokine receptors (CCR) is thought to mediate leukocyte migration, the expression
pattern of chemokines and CCR in a model of IC-GN was examined. The transient course
and predominant glomerular pathology of this model allows the examination of both the
induction and resolution phases of IC-GN. GN was induced in mice by daily apoferritin …