Epithelial galectin-3 during human nephrogenesis and childhood cystic diseases.
PJ Winyard, Q Bao, RC Hughes… - Journal of the American …, 1997 - journals.lww.com
Galectin-3 is a beta-galactoside-binding protein with putative roles in development,
oncogenesis, and inflammation. Its expression in human nephrogenesis has not been
previously reported. This study examines galectin-3 expression in early human embryos by
Western blot and immunohistochemistry. This 33-kD protein was detected in the apical
domain of distal tubules of the mesonephros and also in the mesonephric duct. In the
metanephros, the adult kidney precursor, galectin-3 was detected in the apical domains of …
oncogenesis, and inflammation. Its expression in human nephrogenesis has not been
previously reported. This study examines galectin-3 expression in early human embryos by
Western blot and immunohistochemistry. This 33-kD protein was detected in the apical
domain of distal tubules of the mesonephros and also in the mesonephric duct. In the
metanephros, the adult kidney precursor, galectin-3 was detected in the apical domains of …
