The role of growth factors in the pituitary
S Ezzat, S Melmed - Journal of endocrinological investigation, 1990 - Springer
S Ezzat, S Melmed
Journal of endocrinological investigation, 1990•SpringerEGF is an ubiquitous polypeptide with potent mitogenic (2) as well as growth inhibitory
effects (3) on a variety of cell types. EGF receptors are expressed on GH rat pituitary cell
lines (4), primary rat (5), and normal human pituitary cells (6). These binding sites are
located predominantly on lactotrophs, somatotrophs, and thyrotrophs (5). As with
extrapituitary EGF receptors, male rat pituitary cells possess nearly twice the binding as cells
derived from females
effects (3) on a variety of cell types. EGF receptors are expressed on GH rat pituitary cell
lines (4), primary rat (5), and normal human pituitary cells (6). These binding sites are
located predominantly on lactotrophs, somatotrophs, and thyrotrophs (5). As with
extrapituitary EGF receptors, male rat pituitary cells possess nearly twice the binding as cells
derived from females
EGF is an ubiquitous polypeptide with potent mitogenic (2) as well as growth inhibitory effects (3) on a variety of cell types. EGF receptors are expressed on GH rat pituitary cell lines (4), primary rat (5), and normal human pituitary cells (6). These binding sites are located predominantly on lactotrophs, somatotrophs, and thyrotrophs (5). As with extrapituitary EGF receptors, male rat pituitary cells possess nearly twice the binding as cells derived from females
Springer