The 1982 revised criteria for the classification of systemic lupus erythematosus

EM Tan, AS Cohen, JF Fries, AT Masi… - … : Official Journal of …, 1982 - Wiley Online Library
EM Tan, AS Cohen, JF Fries, AT Masi, DJ Mcshane, NF Rothfield, JG Schaller, N Talal
Arthritis & Rheumatism: Official Journal of the American College …, 1982Wiley Online Library
The 1971 preliminary criteria for the classification of systemic lupus erythematosus (SLE)
were revised and updated to incorporate new immunologic knowledge and improve disease
classification. The 1982 revised criteria include fluorescence antinuclear antibody and
antibody to native DNA and Sm antigen. Some criteria involving the same organ systems
were aggregated into single criteria. Raynaud's phenomenon and alopecia were not
included in the 1982 revised criteria because of low sensitivity and specificity. The new …
Abstract
The 1971 preliminary criteria for the classification of systemic lupus erythematosus (SLE) were revised and updated to incorporate new immunologic knowledge and improve disease classification. The 1982 revised criteria include fluorescence antinuclear antibody and antibody to native DNA and Sm antigen. Some criteria involving the same organ systems were aggregated into single criteria. Raynaud's phenomenon and alopecia were not included in the 1982 revised criteria because of low sensitivity and specificity. The new criteria were 96% sensitive and 96% specific when tested with SLE and control patient data gathered from 18 participating clinics. When compared with the 1971 criteria, the 1982 revised criteria showed gains in sensitivity and specificity.
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