An assay for the quantitative measurement of in vitro phagocytosis of early apoptotic thymocytes by murine resident peritoneal macrophages
R Licht, CWM Jacobs, WJM Tax, JHM Berden - Journal of immunological …, 1999 - Elsevier
Research into the mechanisms by which apoptotic cells are phagocytosed has grown
considerably over recent years, together with a growing appreciation of the importance of
clearance of redundant cells for tissue homeostasis. However, studies addressing the
efficacy of phagocytosis have been rare. The few studies reported to date were either
attempts to determine apoptotic cell clearance from the circulation or were focused on
clearance in inflammation. We now describe an in vitro assay which permits the quantitative …
considerably over recent years, together with a growing appreciation of the importance of
clearance of redundant cells for tissue homeostasis. However, studies addressing the
efficacy of phagocytosis have been rare. The few studies reported to date were either
attempts to determine apoptotic cell clearance from the circulation or were focused on
clearance in inflammation. We now describe an in vitro assay which permits the quantitative …