Inhibition of effects of endogenously synthesized histamine disturbs in vitro human dendritic cell differentiation
JB Szeberényi, É Pállinger, M Zsinkó, Z Pós, G Rothe… - Immunology letters, 2001 - Elsevier
Histamine, a principal mediator in various physiological and pathological cell functions is
synthesized from l-histidine exclusively by histidine decarboxylase, an enzyme, which is
expressed in many tissues of mammalian organism. Histamine plays a role in various
cellular functions, including cell differentiation. The aim of this study was to determine the
presence and to characterize the role of the endogenously produced histamine during in
vitro dendritic cell (DC) differentiation induced by interleukin-4 (IL-4) and granulocyte …
synthesized from l-histidine exclusively by histidine decarboxylase, an enzyme, which is
expressed in many tissues of mammalian organism. Histamine plays a role in various
cellular functions, including cell differentiation. The aim of this study was to determine the
presence and to characterize the role of the endogenously produced histamine during in
vitro dendritic cell (DC) differentiation induced by interleukin-4 (IL-4) and granulocyte …
