Suppression of experimental allergie encephalomyelitis in offspring of DA and Wistar rats following immunization of mother with encephalitogen
M Dimitrijević, BM Marković, O Laban… - Journal of …, 1995 - Elsevier
Immunization of female rats with encephalitogen before gestation, during gestation, and
during lactation differentially decreased susceptibility to experimental allergic
encephalomyelitis (EAE) in their offspring. The most pronounced suppression, revealed by
lowered incidence and weaker clinical signs of the disease, was observed in offspring of
mothers immunized before gestation and during lactation in both Dark August (EAE-
susceptible), and Wistar (EAE-relatively resistant) rat strains. Induction of EAE in mothers …
during lactation differentially decreased susceptibility to experimental allergic
encephalomyelitis (EAE) in their offspring. The most pronounced suppression, revealed by
lowered incidence and weaker clinical signs of the disease, was observed in offspring of
mothers immunized before gestation and during lactation in both Dark August (EAE-
susceptible), and Wistar (EAE-relatively resistant) rat strains. Induction of EAE in mothers …