[HTML][HTML] Hepatocellular ATP-binding cassette protein expression enhances ATP release and autocrine regulation of cell volume
RM Roman, Y Wang, SD Lidofsky… - Journal of Biological …, 1997 - ASBMB
In a model liver cell line, recovery from swelling is mediated by a sensitive autocrine
pathway involving conductive release of ATP, P 2 receptor stimulation, and opening of
membrane Cl− channels (Wang, Y., Roman, RM, Lidofsky, SD, and Fitz, JG (1996) Proc.
Natl. Acad. Sci. USA 93, 12020–12025). However, the mechanisms coupling changes in cell
volume to ATP release are not known. Based on evidence that certain ATP-binding cassette
(ABC) proteins may function as ATP channels or channel regulators, we evaluated the …
pathway involving conductive release of ATP, P 2 receptor stimulation, and opening of
membrane Cl− channels (Wang, Y., Roman, RM, Lidofsky, SD, and Fitz, JG (1996) Proc.
Natl. Acad. Sci. USA 93, 12020–12025). However, the mechanisms coupling changes in cell
volume to ATP release are not known. Based on evidence that certain ATP-binding cassette
(ABC) proteins may function as ATP channels or channel regulators, we evaluated the …