Scavenger receptors in innate immunity

AM Pearson - Current opinion in immunology, 1996 - Elsevier
AM Pearson
Current opinion in immunology, 1996Elsevier
Scavenger receptors are cell-surface proteins expressed by mammalian monocytes and
macrophages and by invertebrate hemocytes, among other cell types. They exhibit
distinctive ligand-binding properties, recognizing a wide range of ligands that include
microbial surface constituents and intact microbes. The ligand-binding properties and
expression patterns of these receptors suggest that they may function in one or more host-
defense-related processes. Significant advances in scavenger receptor biology have …
Scavenger receptors are cell-surface proteins expressed by mammalian monocytes and macrophages and by invertebrate hemocytes, among other cell types. They exhibit distinctive ligand-binding properties, recognizing a wide range of ligands that include microbial surface constituents and intact microbes. The ligand-binding properties and expression patterns of these receptors suggest that they may function in one or more host-defense-related processes. Significant advances in scavenger receptor biology have recently been reported, including the identification of several new scavenger receptor genes.
Elsevier