B1 cells: similarities and differences with other B cell subsets
F Martin, JF Kearney - Current opinion in immunology, 2001 - Elsevier
F Martin, JF Kearney
Current opinion in immunology, 2001•ElsevierSince their discovery, B1 B cells' origins and developmental pathways have eluded
characterization. In the past year, focus on B1 B cells has shifted dramatically from
developmental to functional aspects of these cells. Most advances have been made in
describing the physiological activities of B1 cells, including their migration, activation by
antigen and role in both autoimmunity and malignancy.
characterization. In the past year, focus on B1 B cells has shifted dramatically from
developmental to functional aspects of these cells. Most advances have been made in
describing the physiological activities of B1 cells, including their migration, activation by
antigen and role in both autoimmunity and malignancy.
Since their discovery, B1 B cells’ origins and developmental pathways have eluded characterization. In the past year, focus on B1 B cells has shifted dramatically from developmental to functional aspects of these cells. Most advances have been made in describing the physiological activities of B1 cells, including their migration, activation by antigen and role in both autoimmunity and malignancy.
Elsevier