Regulation of FAT/CD36 gene expression: further evidence in support of a role of the protein in fatty acid binding/transport

Z Sfeir, A Ibrahimi, E Amri, P Grimaldi… - … leukotrienes and essential …, 1997 - Elsevier
Much biochemical evidence has implicated rat adipocyte CD36 (FAT) in membrane binding
and transport of long-chain fatty acids (FA). Expression of the mRNA favored tissues with
active FA metabolism and was upregulated in vivo with diabetes and with high fat feeding. In
culture, CD36 mRNA was a strong marker of preadipocyte differentiation and was
modulated by the same factors effective on mRNAs coding for other proteins involved in FA
metabolism. In preadipocytes, long-chain FA or 2-bromopalmitate but not short-chain FA …