[HTML][HTML] Heat Shock-sensitive Expression of Calreticulin.: IN VITRO AND IN VIVO UP-REGULATION
EM Conway, L Liu, B Nowakowski… - Journal of Biological …, 1995 - ASBMB
Calreticulin (CRT) is an ubiquitous, highly conserved, Ca 2+-binding protein of the
sarcoplasmic and endoplasmic reticulum. The precise function (s) of CRT is unknown.
However, based on sequence analyses and observations that it may bind to steroid
receptors and integrins and store Ca 2+ within the cell, it has been postulated to play a"
housekeeping" role. To determine whether the level of expression of CRT is affected by
stress, we examined the heat shock response of CRT from a variety of cultured cells …
sarcoplasmic and endoplasmic reticulum. The precise function (s) of CRT is unknown.
However, based on sequence analyses and observations that it may bind to steroid
receptors and integrins and store Ca 2+ within the cell, it has been postulated to play a"
housekeeping" role. To determine whether the level of expression of CRT is affected by
stress, we examined the heat shock response of CRT from a variety of cultured cells …