Epidermal growth factor reproduces many of the effects of estrogen on the murine female
reproductive tract and may partially mediate estrogen-induced growth and differentiation.
The mechanism by which the actions of estrogens and epidermal growth factor (EGF)
converge is unknown. The studies described herein were performed to investigate the
possibility that some of the actions of EGF may be mediated through the estrogen receptor. A
specific estrogen receptor (ER) antagonist inhibited estrogenlike effects of EGF in the mouse …