[HTML][HTML] Functional characterization of domains contained in hepatocyte growth factor-like protein

SE Waltz, SA McDowell, RS Muraoka, EL Air… - Journal of Biological …, 1997 - ASBMB
To delineate the functional protein domains necessary for the biological activity of
hepatocyte growth factor-like protein (HGFL), we created various site-directed and deletion
mutated cDNAs coding for this protein. Wild-type and mutated versions of HGFL were
produced after transfection of the corresponding cDNAs into tissue culture cells. The
biological importance of the domains within HGFL was then examined by addition of
recombinant wild-type or mutant forms of HGFL to assays aimed at elucidating regions …