[HTML][HTML] The Receptor for Advanced Glycation End Products (RAGE) Is a Cellular Binding Site for Amphoterin: Mediation of neurite outgrowth and co-expression of …

O Hori, J Brett, T Slattery, R Cao, J Zhang… - Journal of biological …, 1995 - ASBMB
The receptor for advanced glycation end products (RAGE), a newly-identified member of the
immunoglobulin superfamily, mediates interactions of advanced glycation end product
(AGE)-modified proteins with endothelium and other cell types. Survey of normal tissues
demonstrated RAGE expression in situations in which accumulation of AGEs would be
unexpected, leading to the hypothesis that under physiologic circumstances, RAGE might
mediate interaction with ligands distinct from AGEs. Sequential chromatography of bovine …