Apoptosis signaling in lymphocytes.
C Scaffidi, S Kirchhoff, PH Krammer… - Current opinion in …, 1999 - europepmc.org
C Scaffidi, S Kirchhoff, PH Krammer, ME Peter
Current opinion in immunology, 1999•europepmc.orgLymphocyte apoptosis is essential for proper function of the immune system. Among other
functions, it is responsible for the homeostasis of immune cells and plays a key role in the
elimination of autoreactive lymphocytes. Recently, progress has been made in the
identification of genes that regulate apoptosis. Studies characterizing the basic apoptosis
signaling machinery have begun to reveal the molecular control of processes that modulate
lymphocyte apoptosis.
functions, it is responsible for the homeostasis of immune cells and plays a key role in the
elimination of autoreactive lymphocytes. Recently, progress has been made in the
identification of genes that regulate apoptosis. Studies characterizing the basic apoptosis
signaling machinery have begun to reveal the molecular control of processes that modulate
lymphocyte apoptosis.
Lymphocyte apoptosis is essential for proper function of the immune system. Among other functions, it is responsible for the homeostasis of immune cells and plays a key role in the elimination of autoreactive lymphocytes. Recently, progress has been made in the identification of genes that regulate apoptosis. Studies characterizing the basic apoptosis signaling machinery have begun to reveal the molecular control of processes that modulate lymphocyte apoptosis.
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