[PDF][PDF] Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice
H Mizuno, C Sakamoto, K Matsuda, K Wada… - …, 1997 - researchgate.net
The rate-limiting steps in eicosanoid biosynthesis are See editorial on page 645. not only
the liberation of arachidonic acid (AA) from membrane glycerophospholipids but also the
conversion Background & Aims: The role of two forms of cyclooxy- of AA to PG by PG
endoperoxide synthase/COX. Several genase (COX-1 and COX-2) in gastric mucosal
lesions recent studies have confirmed the presence of two forms of is not well understood.
The regulation of both forms of
the liberation of arachidonic acid (AA) from membrane glycerophospholipids but also the
conversion Background & Aims: The role of two forms of cyclooxy- of AA to PG by PG
endoperoxide synthase/COX. Several genase (COX-1 and COX-2) in gastric mucosal
lesions recent studies have confirmed the presence of two forms of is not well understood.
The regulation of both forms of