[CITATION][C] Metastases in carcinoma. Analysis of 1000 autopsied cases

HL Abrams, R Spiro, N Goldstein - Cancer, 1950 - Wiley Online Library
HL Abrams, R Spiro, N Goldstein
Cancer, 1950Wiley Online Library
METHODS One-thousand consecutive cases of malignant neoplasms of epithelial origin
were analyzed for the incidence of metastases. These cases were examined in the
postmortem state at Montefiore Hospital between 1943 and 1947. Malignant neoplasms of
nonepithelial origin were not included because of the controversy about the unicentric or
multicentric origin of such tumors as lymphoma and because of the frequent uncertainty as
to the primary site. Direct extension of carcinoma to adjacent organs was excluded as …
METHODS
One-thousand consecutive cases of malignant neoplasms of epithelial origin were analyzed for the incidence of metastases. These cases were examined in the postmortem state at Montefiore Hospital between 1943 and 1947. Malignant neoplasms of nonepithelial origin were not included because of the controversy about the unicentric or multicentric origin of such tumors as lymphoma and because of the frequent uncertainty as to the primary site. Direct extension of carcinoma to adjacent organs was excluded as carefully as possible. Metastases to the capsules of organs, such as liver and spleen, were not considered organ metastases, but rather peritoneal metastases. The material was then collected in tabular form to indicate the percentage of involvement of organs by the entire group of neoplasms and the fre-
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